Journal: Frontiers in Neuroscience
Article Title: Software for near-real-time voltammetric tracking of tonic neurotransmitter levels in vivo
doi: 10.3389/fnins.2022.899436
Figure Lengend Snippet: Software user interface. (A) Buttons to control the GUI, output text file name, and current scan count. (B) Plot of waveform applied to the electrode at the beginning of each scan. (C) The raw redox current trace response to the input waveform. (D) Non-Faradaic-subtracted voltammogram as a function of input voltage. (E) A 3D color plot of the non-Faradaic-subtracted voltammogram plotting input voltage on the X -axis, the amount that the input voltage is swept through with each square wave on the Y -axis, and current as the intensity. The bottom half plots oxidation currents, and the left half plots current response to the upward sweep of each square wave. (F) User-defined fitting, filtering, kernel, and thresholding parameters. (G) Charge trace which tracks the analyte charge computed for each scan. For this experiment, nomifensine was administered at scan 225. (H) Left: Real-time dopamine kernel used for charge calculation. Dashed line indicates the area used for charge computation. Right: 3D color plots of pre-nomifensine (scan 175) and post-nomifensine (scan 450) states.
Article Snippet: The developed software was based within a MATLAB Application Designer GUI linked to several MATLAB helper scripts for data processing.
Techniques: Software